Channelopathy pathogenesis in autism spectrum disorders
نویسندگان
چکیده
منابع مشابه
Channelopathy pathogenesis in autism spectrum disorders
Autism spectrum disorder (ASD) is a syndrome that affects normal brain development and is characterized by impaired social interaction as well as verbal and non-verbal communication and by repetitive, stereotypic behavior. ASD is a complex disorder arising from a combination of multiple genetic and environmental factors that are independent from racial, ethnic and socioeconomical status. The hi...
متن کاملautism spectrum disorders in iran
how to cite this article: mohammadi mr, salmanian m, akhondzadeh sh. autism spectrum disorders in iran. iranian journal of child neurology2011;5(4):1-9. objective autistic disorder, asperger syndrome, and pdd-not otherwise specified are subsets of autism spectrum disorders (asds), which are characterized by impairments in social communication and stereotyped behavior. this article reviews the p...
متن کاملImmune related factors in pathogenesis of autism spectrum disorders.
OBJECTIVE Etiology of Autism Spectrum Disorders (ASD) is insufficiently known. It is suggested that genes play a crucial role in ASD but additional environmental factors to exacerbate the syndrome are needed. Recently, the inflammatory factors in ASD that may predispose to the disorder attract a great attention. Therefore, the aim of this article was to review the literature on the possible ass...
متن کاملMicroglia in the pathogenesis of autism spectrum disorders.
Proper synaptic pruning is essential for the development of functional neural circuits. Impairments in synaptic pruning disrupt the excitatory versus inhibitory balance (E/I balance) of synapses, which may cause neurodevelopmental disorders such as autism spectrum disorder (ASD). Recent studies have determined molecular mechanisms by which microglia, the brain's resident immune cells, engulf in...
متن کاملEconomic burden of autism spectrum disorders in Iran
Background: The prevalence of autism spectrum disorder (ASD) as a child neurodevelopmental disorder has increased significantly during the past 3 decades worldwide and in Iran. This chronic disease does not cause premature death and there is no definitive treatment. Thus, the cost of ASD is extremely heavy and overwhelming. The purpose of this study is to calculate the economic burden of ASD in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2013
ISSN: 1664-8021
DOI: 10.3389/fgene.2013.00222